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wolfdancer
11-18-2004, 02:39 PM
was previously thought:
Humans have just 20,000 to 25,000 genes - well down on previous estimates of 27,000 to 40,000, says the latest analysis of the gene-containing portion of the human genome.

And a separate study has found detailed flaws in “shotgun” sequencing, the more rapid of the two methods used to sequence genomes.

The latest gene count reveals that researchers overestimated the number of genes lurking in heavily-duplicated regions of the human genome, which are extremely tricky to sequence because they are repeated DNA sequences.

“Finding the genes is hard, even in a finished sequence,” says Bob Waterston of the University of Washington in Seattle, US, and a lead author of the latest genome analysis.

“But the main point is that we have the genome correct now,” he says. “We’ve got through the many hard parts of the genome, and these included recently duplicated segments which were impossible to study in the earlier drafts.”